Biology

• E. coli Model for Protein Amplification Escherichia coli is a bacterium that most of us know first from recalls of foods like meat and lettuce. Although E. coli is a commensal (non-harmful) gut bacterium, the wrong circumstance and strain can make infection uncomfortable and dangerous. E. coli is gram negative, meaning it has a double-layered cell membrane that makes it more difficult to treat with antibiotics. Our homogenization equipment is regularly used to. [more]

  by JessicaGenizer, Biology,

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• Pharmaceutical Giants Rush to Develop PD-(L)1 Bispecific Antibodies: A New Battlefield in Immunotherapy In recent years, immune checkpoint inhibitors (ICIs) have emerged as a significant breakthrough in cancer therapy, reshaping traditional treatment paradigms. PD-1/PD-L1 pathway inhibitors have been widely used across various cancer treatments, demonstrating impressive efficacy. As PD-(L)1 inhibitor therapies continue to mature, pharmaceutical giants have turned their. [more]

  by sherwinbrown, Biology,

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• New Insights Into the Pathogenesis and Diagnosis of Rheumatoid Arthritis The hallmark of rheumatoid arthritis (RA) is erosive arthritis, an autoimmune disease that ultimately results in joint deformities and functional loss. It can also be complicated by pulmonary disease, cardiovascular disease, malignant tumors, and depression. The etiology of RA remains unclear. However, infections have been suggested as environmental triggers in as many as 20% of patients. Due to. [more]

  by sherwinbrown, Biology,

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• Decoding Cellular Signals: The Power of Phosphorylation Antibody Arrays in Modern Biology Inside every cell, complex communication networks are constantly at work. These systems—known as signaling pathways—allow cells to respond to changes in their environment, control growth, defend against threats, and carry out essential biological tasks. One of the key methods cells use to transmit signals is phosphorylation, a process where a phosphate group is added to a. [more]

  by sherwinbrown, Biology,

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• From IgE to IgA: New Antibody Frontiers in Allergen Immunotherapy Allergic diseases such as asthma and allergic rhinitis affect billions of people around the world, often reducing quality of life and straining healthcare systems. Traditional treatments—including antihistamines and corticosteroids—primarily aim to control symptoms, but they don’t address the underlying immune dysfunction that causes allergic reactions. This is where allergen immunotherapy. [more]

  by sherwinbrown, Biology,

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• Single-Cell CyTOF and Multi-Omics: Decoding the Complexity of Life One Cell at a Time In recent years, single-cell analysis has emerged as a powerful approach to dissect the biological heterogeneity that exists even within a seemingly uniform population of cells. Two cutting-edge technologies—single-cell mass cytometry (CyTOF) and single-cell multi-omics—are leading the way in helping researchers understand how cells function, interact, and change over time in. [more]

  by sherwinbrown, Biology,

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• Complement testing evaluates the immune system’s functionality by analyzing pathways and protein activity. It includes assays for classical, lectin, and alternative pathways, as well as detection of activation products and genetic variants. These tests support research in autoimmune disorders, inflammation, and therapeutic development by offering insights into complement regulation, deficiencies, and inhibitor efficacy across diverse biological. [more]

  by cailynnjohnson, Biology,

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• https://www.genizer.com/nanogenizer-dual_p0044.html Portable Laboratory Dual-Pump testing up to 30,000 psi with electric power. Application: Nanodispersions, nanoemulsions and nanotube Cell disruption Micro/nanoencapsulation in polymers, liposomes and oils Solid dispersion and suspension, deagglomeration Performance: Energy efficient, 1/2 energy loss of the most homogenizers Small (integrated design delivers the light weight and small dimensions) Smart. [more]

  by JenniferGenizer, Biology,

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• The advantage of Genizer liposome extruders Genizer offers a comprehensive range of extruders suitable for researchers and manufacturers across all scales, from lab-scale HandExtruder and GJE-10mL/100mL models for small-scale research and development, to pilot-scale GJE-800mL/3000mL models for larger experiments and production runs, and the GOE-8L/25L extruder for large-scale commercial production. This means that regardless of the scale of the project, Genizer has an. [more]

  by JessicaGenizer, Biology,

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• Scaling with Genizer: Homogenizers At Genizer, we want our equipment to be with you every step of the way! That’s why we make equipment that squeezes into an academic lab all the way up to manufacturing. Here’s the High-Pressure Homogenization equipment that can take you all the way to capacity. HandGenizer For a more portable solution to high-pressure homogenization, we have the HandGenizer. Well suited to long-term storage, the HandGenizer is great in an. [more]

  by JessicaGenizer, Biology,

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• Mouse Kidney Epithelial Cells play a vital role in renal function and are widely used in biomedical research for studying kidney development, disease modeling, drug testing, and tissue regeneration. Explore how these cells, isolated through specialized protocols, aid in understanding renal physiology and pathologies like acute kidney injury and chronic kidney disease. Kosheeka provides high-quality, characterized primary kidney epithelial cells to support advanced renal. [more]

  by kosheekaa, Biology,

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• The NanoGenizer | A High-Pressure Homogenizer for Laboratory Settings The NanoGenizer is the most popular unit from Genizer. This high-pressure homogenizer is perfect for laboratory settings because of its compact and energy efficient design.  The NanoGenizer is simple to use. It plugs into the wall and has a convenient touch screen with an auto-stop function. The body of the NanoGenizer serves as the engine to power the ceramic piston. The sample travels in. [more]

  by JessicaGenizer, Biology,

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• 3 Questions to Choose a Liposome Extruder 3 Questions to Ask While Looking for a Liposome Extrusion Option There are three questions to ask when you are choosing a liposome extrusion option. First, what pore size do you need? While a solo homogenizer reaches a liposome size of 20-30nm, any option with extrusion allows for more choice. Second, what power types do you have access to? The jacketed liposome extruders allow for gas power. An electric option is available. [more]

  by JessicaGenizer, Biology,

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• Dual-Light Nano Particle Sizer Laser Particle Sizer especially designed for submicron, nanoemulsions and nano particle size testing. Principle: Dynamic Light Scattering (DLS) https://www.genizer.com/dual-light-nano-particle-sizer_p0033.html You can visit our official website to get more information you want if you are interested in our products.. [more]

  by JessicaGenizer, Biology,

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• Pancreatic β-islet cells secrete insulin and are critical in the regulation of glucose homeostasis. Their dysfunction causes diabetes mellitus, turning these cells into the focal point of research. Exogenous insulin and insulin-regulating medications have been introduced as the first line of treatment. Kosheeka provides customized human and animal primary pancreatic β-islet cells to enhance your research and accelerate the drug development. [more]

  by kosheekaa, Biology,

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